Theorylytics

Molecular Prime

Used by Nova

Ability4
Energy25

Molecular Prime

Primes all enemies in an expanding radius with volatile antimatter. Press the ability to slow down enemy movement, hold the ability to speed them up.

Introduced in Update 9.0 (2013-07-13)

Ability stats

Strength
  • See in-game / wiki ability card for rank values
Duration
  • See in-game / wiki ability card for rank values
Range
  • See in-game / wiki ability card for rank values
Misc
  • Primes all enemies in an expanding radius with volatile antimatter.

Info

  • Molecular Prime is Nova’s ability 4.
  • Primes all enemies in an expanding radius with volatile antimatter.
  • Use it with the rest of the kit — especially Null Star, Antimatter Drop — instead of casting it in isolation.
  • Ability Strength, Duration, Range, and Efficiency each matter differently; check Mod Scaling below before dumping all four.

Augment

9

Molecular Fission

Molecular Prime Augment: Enemies hit by Null Stars are primed. When killed, primed enemies will restore a Null Star charge and have a 100…

Nova
Open augment →
Molecular Fission

Molecular Prime Augment: Enemies hit by Null Stars are primed. When killed, primed enemies will restore a Null Star charge and have a 100% chance of restoring two.

Max rank drain ~9; see rank table on the augment page.

Open full augment page →

Cast Changes

  1. Modifies Molecular Prime with: Molecular Prime Augment: Enemies hit by Null Stars are primed.
  2. Rank up the augment to unlock the full effect values.
  3. Costs a mod slot (and capacity) — only equip it when the change matters for your loop.

Worth the Slot?

  1. Worth it when the augment’s change is central to how you play Nova.
  2. Skip it if the base Molecular Prime already does what you need and you’d rather keep the slot for survivability or strength.

Tips & Tricks

  • Read the battlefield first — cast Molecular Prime when it actually solves the room, not on cooldown habit.
  • Pair Molecular Prime with movement and energy economy so you’re not stranded after a big spend.
  • On Steel Path, confirm whether Molecular Prime still carries without strip, Viral, or a squad buff.
  • If you never press 4, it’s the first Helminth candidate on Nova.

Ability dossier · Molecular Prime

Verified 2026-07-22

Synergies

  • Molecular PrimeNull Star

    Use Molecular Prime to set up Null Star, or follow Null Star with Molecular Prime while enemies are vulnerable.

  • Molecular PrimeAntimatter Drop

    Use Molecular Prime to set up Antimatter Drop, or follow Antimatter Drop with Molecular Prime while enemies are vulnerable.

  • Molecular PrimeWormhole

    Use Molecular Prime to set up Wormhole, or follow Wormhole with Molecular Prime while enemies are vulnerable.

Mod Scaling

Strength

Strength matters if Molecular Prime scales effect power; otherwise dump it for other stats.

Duration

Duration is low priority on Molecular Prime unless an augment or lingering effect needs it.

Range

Increases Molecular Prime’s reach, radius, or targeting distance.

Efficiency

Molecular Prime costs energy each cast — Efficiency (or strong regen) keeps the loop comfortable on long missions.

Priority

Stack the stats that actually move this ability’s needle, then Efficiency for uptime.

Mission Use Cases

MissionHow to Use It
Steel Path Survival / Defense / DisruptionTest whether Molecular Prime still clears or enables clear when enemies are dense and overlevelled.
Mobile Defense / ExcavationUse Molecular Prime to control or delete the swarm on the objective, then reposition.
Exterminate / Capture Speed RunsCast Molecular Prime only when it saves time — skip it on empty tiles.
Spy / Rescue / Quiet RoutesIf Molecular Prime is loud or forces combat, save it for after the vault; if it’s stealth-friendly, use it to stay safe.

Comparisons

  • VS

    Vs similar tools on other frames — Molecular Prime is tuned for Nova’s loop — don’t judge it as a standalone subsume without the rest of the kit.

Other Nova abilities